Technology
Our biochip is a versatile, cutting-edge biosensing platform that deeply integrates microfluidics with semiconductor technology, enabling rapid and highly sensitive detection of trace amounts of DNA, RNA, proteins, antibodies, pathogens, and any other biomolecular fragments.
Our core technology is the Silicon Nanowire Field-Effect Transistor (SiNW-FET) chip, developed based on Bio-FET (Biological Field-Effect Transistor) technology. This label-free and amplification-free sensor combines nanowires with biological probes to detect pA-level ultra-trace current changes caused by probe–analyte binding events, enabling ultra-high-sensitivity detection.
Features of Bio-FET
High Surface-to-Volume Ratio
Using a nanoscale design to maximize contact with biomolecules to boost sensitivity.
Label-Free Detection
Detects molecular binding directly without fluorescent or enzymatic labels to simplify workflows.
Amplication Free
No PCR or amplification required, yet accurately detects ultra-low concentration samples for clinical and liquid biopsy use.
Real-Time Detection
Provide real-time binding signals for dynamic monitoring and rapid testing.
Compact Design
Enable easy integration with portable devices for on-site diagnostics.
Bio-FET vs. Traditional Methods
| Feature | Bio-FET Chip | PCR | ELISA |
|---|---|---|---|
| Requires Labeling | No | Yes | Yes |
| Turnaround Time | < 0.5 hours | 1–4 hours | 2–5 hours |
| Real-Time Detection | Yes | No | No |
| System Integration | High | Low | Low |
Bio-FET technology drastically reduces time, complexity, and cost compared to conventional PCR and ELISA, making it ideal for point-of-care diagnostics and automated workflows.
Applications
Our biochips can be widely applied in various medical and defense settings, with rapid deployment capability in airports, seaports, forward operating bases, and other high-security or public venues, to identify carriers or implement preventive isolation before infected individuals become contagious:
✓ Infectious Disease Diagnostics (e.g., COVID-19, influenza)
✓ Cancer Biomarker Detection for early screening
✓ Rapid bacteria classification without culture
✓ Environmental and Food Safety Testing
✓ Neurodegenerative Disease Research (e.g., Alzheimer’s)